L-Leucine

                       

PRODUCT DETAILS:

·      Pure pharmaceutical grade L-Leucine.
·      Product packed in a food grade re-sealable foil bag for freshness.
·      Serving suggestion: The typically recommended dose for L-Leucine varies between 1 grams and 3 grams per single dose taken 2 or 3 times per day for a total combined daily dose of between 2 grams and 9 grams.
·      Our L-Leucine is 100% pure, no fillers, additives or sugars.
·      Best before DEC 2013.

About L-Leucine:

L-Leucine, or also known as Leucine, is an essential branched-chain amino acid (BCAA) that comprises about eighty percent of the total amino acid count in the body's protein structures. Being an essential amino acid and as one of the three BCAA's (that includes isoleucine and valine), this means everyone needs Leucine to maintain basic health, as it is not synthesized in the body. Athletes who are engaged in strenuous activity, under extreme pressure, or at high altitudes require high amounts of this nutrient either from dietary sources, supplementation, or both. L-Leucine helps in the production of energy in the body and has been found experimentally to reduce twitching and tremors in animals. People who exercise a lot, have a low-protein diet, or are seriously trying to build muscle mass should consider leucine supplementation. Although Leucine is also available in stand-alone supplemental form, it should always be taken together with the other two branched-chain amino acids, isoleucine and valine. To make the most out of this supplement, the ideal balance is at two parts L-Leucine for every two parts L-Valine and for every one part of L-Isoleucine. Good natural sources of leucine include brown rice and beans, all types of meats and poultry, cheese, nuts, whole wheat, and soy flour. 

One of the main functions of Leucine is in regulating protein metabolism in the body. The availability of leucine is of critical importance in controlling the net synthesis of protein. Therapeutically, leucine, together with the other BCAAs isoleucine and valine, can be used as a means of minimizing protein loss which may lead to muscle wasting and atrophy in patients undergoing surgery. Due to the fact that it has athletic applications, L-Leucine is now widely used as an ingredient in supplements for muscle building because of its many beneficial effects on sports performance. It helps preserve lean muscle tissue, it supplies the body with energy when under stress (i.e. during intense athletic activity), it keeps muscle glycogen (glucose stored in muscle tissue used to power muscular contraction) and nitrogen balance in check, and it enhances cognitive and thinking abilities that can decline or would otherwise be clouded as physical activity becomes more intense. 

In the diet, the effects of L-Leucine are profound. As the strongest of the BCAA's, L-Leucine is what's known as a "limiting nutrient", which means one must have enough L-Leucine relative to other amino acids to enable your body to make use of what you eat. Simply put, if you suffer from an L-Leucine deficiency, your body will not be able to make use of the protein that you give it, regardless of how often or how much protein you consume. Unless you have adequate L- Leucine, the money used on quality food and dietary supplements will be for nothing. To make the most of what you eat, you need two parts L-Leucine and two parts L-Valine for every one part of L-Isoleucine to get optimal results. 

BCAAs (branched chain amino acids) - L-leucine, L-isoleucine and L-valine - are undoubtedly the single most important group of amino acids for just about anyone, from world champion athletes to regular people. All the three amino acids with branching side chains work together inside the body and protect muscle or act as fuel in the biochemistry of the body. The body uses these to promote healing of injured tissues, to speed up recovery, and to protect against muscle tissue breakdown (catabolism) during exercise. As such, they are all normally recommended for people recovering from surgery, as they tend to increase the rate of healing in the body. BCAAs are one third of all the protein in muscles, therefore extremely important for developing and building muscles. Studies have shown BCAA to be helpful in other areas as well, due to what each ingredient does in its own right. For example, Leucine is necessary for wound recovery to skin and bones as well as helps protect muscles, Valine helps promote or maintain nitrogen balance (essential for muscular development), and Isoleucine helps boost energy and is necessary for forming hemoglobin. 

What is L-Leucine used for and who uses it?

Leucine functions best with the amino acids isoleucine and valine in repairing muscles, regulating blood sugar, and providing the body with energy. It also improves and stimulates production of growth hormones, and helps burn visceral fat, adipose tissue located in the deepest layers of the body which are least responsive to dieting and exercise. Because of this, L-Leucine is typically taken by weight lifters and performance athletes wanting to reduce fat and maximize muscle mass. Leucine, isoleucine, and valine are branched-chain amino acids (BCAAs), and all three of them work synergistically to help promote and speed up muscle recovery after exercise. In preventing muscle loss, Leucine is the most effective BCAA of the three because it breaks down and is converted to glucose more quickly than isoleucine and valine. This attribute of leucine of being readily converted to glucose enables it to regulate blood sugar. Increased glucose supplies prevent the body's cannibalization of muscle for energy during intense workouts, so it is no surprise that this amino acid supplement is popular among professional body builders. Leucine also promotes the healing of bones, skin, and muscle tissue after traumatic injury, and this is why it is often recommended for those recovering from surgery. 

Blood levels of L-Leucine will significantly decrease after strenuous exercise and will stay low until complete recovery. Supplementation with L-Leucine one hour before strenuous workouts can shorten the recovery time considerably by increasing muscle protein synthesis and counteracting catabolic processes. Aside from regulating blood-sugar and energy levels, Leucine helps with the growth and repair of muscle tissue (such as bones, skin and muscles), growth hormone production, and wound healing. Individuals who suffer from glucose intolerance may require higher amounts of leucine supplementation because as studies have shown, insulin deficiency results in poor utilization of leucine. Additionally, leucine can also assist to prevent the breakdown of muscle proteins that sometimes occur after trauma or severe stress. 

For athletes, Leucine appears to be the most important BCAA (Branched chain amino acid), as it can affect numerous anabolic hormones, and also has an impact on preventing protein depletion and degradation. Supplementing with L-leucine, L-isoleucine and L-valine, collectively known as BCAAs, can feed your body so that it doesn't eat your own tissue. Aside from being required by the body, BCAAs can also be used to regenerate the skin of burn victims, because they aid in repair, growth, and development of muscle tissue, and to help treat kidney failure and liver disease as well. The combination of these three essential amino acids - L-leucine, L-isoleucine and L-valine makes up approximately 33% of skeletal muscle in the human body, and plays an important role in protein synthesis. BCAAs are currently used primarily for supplementation among strength athletes because it promotes protein synthesis in muscle. When taken during training, BCAAs have been shown to increase both growth hormone (GH) and insulin, thus increasing anabolism and anti-catabolism. Also, unlike other amino acids, BCAAs are used to provide energy and they have been shown to decrease post-workout soreness, which translates to faster recovery times even after intense and grueling training sessions. 

Since BCAAs are so crucial for the proper functioning of muscle tissue, they are very popular with endurance athletes, body builders, and others looking to simply stay healthy. BCAAs are metabolized in the muscle as opposed to the liver, and because of this many body builders and athletes use BCAA supplements while undergoing intense exercise. Even light exercise can cause BCAAs levels to drop quickly which leads to muscle breakdown (catabolism), fatigue, and a drop in testosterone levels. If you are in a building phase in any exercise routine or if you train for long periods of time, BCAAs are a good choice for you to ensure you do not use or burn the muscle you've worked so hard to build to get the energy you require in your strenuous activities. 

What is the daily suggested dose of L-Leucine?

The typically recommended dose for L-Leucine varies between 1 grams and 3 grams per single dose taken 2 or 3 times per day for a total combined daily dose of between 2 grams and 9 grams. One level half tablespoon (one and one half level teaspoons) of L-Leucine will be equivalent to about 2.5 grams. One half level tablespoon taken twice per day, especially taken about 1 hour before workouts, will yield a total daily dose of 5 grams.

Deficiency symptoms and Potential side effects of L-Leucine

The symptoms of either deficiency or excess of leucine are similar to those of patients suffering from hypoglycemia, which may include headaches, dizziness, fatigue, depression, confusion, and irritability. An excessively high intake of leucine is believed to cause and develop pellagra, a deficiency of the vitamin niacin that causes dermatitis, diarrhea, and mental disorders. Too much leucine in the diet can disrupt liver and kidney function because it can significantly increase the amount of ammonia in the body. For this reason, people with impaired liver or kidney function should not take isoleucine without first consulting a physician, as large doses of amino acids may aggravate these conditions. Although no evidence of toxicity has been known and this BCAA is generally considered to be safe for healthy persons, keep in mind that it is always best to consult your physician first before using any dietary supplement, just to be on the safe side. 

Taste, solubility, and suggested preparation of L-Leucine

Pure bulk L-Leucine powder is not easily soluble in water and has a bitter taste. The best way to take L-Leucine powder is mixed, or blended with and suspended within a protein shake.

About Us:

·      We purchase direct from the manufacturer and import all our amino acid products direct therefore cutting out the middle man so we can keep our prices low.

·      We research our products and only sell the best quality products available.

·      We are genuine wholesalers to other Australian businesses.

·      All our products are packaged in Australia in a food approved premises.

Payment:

We accept payments via PAYMATE or BANK DEPOSIT. We are also able to accept money orders and cheques. All orders are sent out after we receive cleared funds.

Shipping:

All orders are sent within 3 business days.

All orders are sent via Aust Post express or courier for bigger orders.

Return Policy

·         Unopened products only may be returned to us for a full refund, minus delivery/return costs

·         We recommend that you pack the item(s) carefully and insure the package, as any items lost or damaged in shipping cannot be refunded

·      After 7 days past your receipt of shipment, no returns are accepted

Power Nutrients make no therapeutic use claims. Therapeutic is defined by the Australian Therapeutic Goods Administration (TGA) as:

1. preventing, diagnosing, curing or alleviating a disease, ailment, defect or injury in persons or animals; or
2. influencing, inhibiting or modifying a physiological process in persons or animals; or
3. testing the susceptibility of persons or animals to a disease or ailment; or
4. influencing, controlling or preventing conception in persons; or
5. testing for pregnancy in persons; or
6. the replacement or modification of parts of the anatomy in persons or animals.

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